Toluidine red - Wikipedia
Toluidine red is an organic compound with the formula C 10 H 6 (OH)(N 2 C 6 H 3 (NO 2)CH 3). A dark red solid, the compound is classified as a azo dye consisting of a 2-naphthol group linked to a 2-nitro-4-methylphenyl substituent. [3] Toluidine red is …
The Laboratory Diagnosis of Syphilis - PMC - National Center for ...
2021年9月20日 · Examples of nontreponemal tests include the Venereal Disease Research Laboratory (VDRL), rapid plasma reagin (RPR), unheated serum reagin (USR), and toluidine red unheated serum test (TRUST) methods (2, 4). As opposed to treponemal tests, nontreponemal tests are quantitative and reported in titers.
Syphilis Testing: Making Sense of Titers | Brown Med-Peds
Toluidine Red Unheated Serum Test (TRUST) Treponemal tests detect antibodies directed against specific treponemal antigens (more specific; typically not detected until ~3 weeks after infection): Fluorescent treponemal antibody absorption (FTA-ABS)
Nontreponemal tests for syphilis - Wikipedia
A nontreponemal test (NTT) is a blood test for diagnosis of infection with syphilis. Nontreponemal tests are an indirect method in that they detect biomarkers that are released during cellular damage that occurs from the syphilis spirochete.
CDC Laboratory Recommendations for Syphilis Testing, United …
2024年2月2日 · The RPR test uses charcoal to aid in detection of the flocculant, and the results can be read macroscopically because the antigen-antibody lattice traps the charcoal particles. The TRUST test uses toluidine red dye in place of charcoal.
Toluidine red unheated serum test, a nontreponemal test for …
Performance of the toluidine red unheated serum test (TRUST) is identical to that of the rapid plasma reagin 18-mm circle card test (U.S. Department of Health, Education, and Welfare, Public Health Service Publication no. 411).
Toluidine red - CAMEO
2022年6月10日 · A line of bright, transparent red synthetic azo-type organic pigments. Toluidine reds are based on the reaction of beta-naphthol with 2-nitro-4-toluidine. Toluidine red was first synthesized in 1904 by Lucius and Brüning in Germany. It reached its peak of …
Toluidine - Wikipedia
The chemical properties of the toluidines are quite similar to those of aniline, and toluidines have properties in common with other aromatic amines. Due to the amino group bonded to the aromatic ring, the toluidines are weakly basic.
Toluidine red | C17H13N3O3 | CID 17047 - PubChem
One of the most widely used of all red pigments on account of the bright scarlet hue, high tinctorial strength, good fastness to acids, alkalis and to light and economy. Some limitation is improved by the relatively poor fastness to organic solvents. Widely used in paints, printing inks, emulsion paints and distempers.
The optimum condition of the toluidine red unheated serum test …
2023年6月12日 · The toluidine red unheated serum test (TRUST) is an alternative to the VDRL test as a serological test for syphilis, but it lacks guidelines for its use in CSF for neurosyphilis diagnosis.