Solid lipid nanoparticles (SLNs) play a crucial role in drug delivery, offering benefits such as enhanced bioavailability, targeted distribution, and reduced toxicity. This article provides a comprehensive overview of SLN formulation, development, ...

2023年9月1日 · The present review briefly introduces SLN and discusses the reasoning behind the use of SLN over other colloidal carriers, such as emulsions and liposomes. Techniques to produce SLN, drug incorporation, loading capacity, and drug release mechanisms are reviewed.

Solid lipid nanoparticles (SLNs) are the first generation of lipid-based nanocarriers that are formulated from lipids, which are solid in the body temperature and stabilized by emulsifiers. SLNs have submicron (less than 1000 nm) sizes.

Solid lipid nanoparticles are at the forefront of the rapidly developing field of nanotechnology with several potential applications in drug delivery, clinical medicine and research, as well as in other varied sciences.

2024年5月16日 · Lipid-based colloidal carriers, particularly Solid Lipid Nanoparticles (SLNs), offer a versatile platform for formulating hydrophobic drugs, presenting significant pharmaceutical implications across diverse fields.

Originating from the work of Gasco [31] and Lucks et al. [32], solid lipid nanoparticles (SLNs) are colloidal particles that leverage a solid lipid matrix for improved drug stability and reduced leakage, showcasing a significant evolution in lipid nanoparticle technology. By definition, SLNs possess inherently small particle sizes.

2024年12月1日 · Lipid nanoparticles (LNPs) have emerged as promising carriers for delivering therapeutic agents, including mRNA-based immunotherapies, in various biomedical applications. The use of LNPs allows for efficient delivery of drugs, resulting in enhanced targeted delivery to specific tissues or cells.

Introduction: Solid lipid nanoparticles (SLNs) are solid core lipid nanocarriers, which can hold both hydrophilic and hydrophobic drugs. They can be made up of biocompatible ingredients and therefore are one of the preferred choices for drug delivery.

Solid lipid nanoparticles (SLNs) are introduced as a carrier system for in effectively water dissolvable medication and corrective dynamic medication. Colloidal particles ranging in size between 10 and 1000 nm are known as nanoparticles.

Solid lipid nanoparticles (SLNs) are gaining significant attention in the pharmaceutical industry due to their biocompatibility and biodegradability, making them a popular functional nanocarrier.