Small nucleolar RNA - Wikipedia
In molecular biology, small nucleolar RNAs (snoRNAs) are a class of small RNA molecules that primarily guide chemical modifications of other RNAs, mainly ribosomal RNAs, transfer RNAs and small nuclear RNAs.
snoRNAs: functions and mechanisms in biological processes, and …
2022年5月12日 · Small nucleolar RNAs (snoRNAs), a type of non-coding RNA, are widely present in the nucleoli of eukaryotic cells and play an important role in rRNA modification.
Small Nucleolar RNAs - Cell Press
Small nucleolar RNAs represent an abundant, evolutionarily ancient group of noncoding RNAs which possess impressively diverse functions ranging from 2′-O-methylation and pseudouridylation of various classes of RNAs, through nucleolytic processing of rRNAs to the synthesis of telomeric DNA.
snoRNAs: functions and mechanisms in biological processes, and …
2022年5月12日 · Small nucleolar RNAs (snoRNAs) are small non-coding RNAs widely present in the nucleoli of eukaryotic cells and have a length of 60–300 nt [1]. snoRNAs are mainly encoded by intronic regions of both protein coding and non-protein coding genes [2].
Non-coding RNAs: lessons from the small nuclear and small nucleolar ...
Recent studies have revealed remarkable complexity in the biogenesis, trafficking and mechanisms of action of small nuclear and small nucleolar ribonucleoproteins (RNPs).
Small nucleolar RNAs: continuing identification of novel members …
2020年4月4日 · Identified five decades ago amongst the most abundant cellular RNAs, small nucleolar RNAs (snoRNAs) were initially described as serving as guides for the methylation and pseudouridylation of ribosomal RNA through direct base pairing.
Small Nucleolar RNA - an overview | ScienceDirect Topics
Small Nucleolar RNA refers to a large class of RNA genes that play a role in processing and modifying other types of RNA, such as tRNAs and snRNAs. They can be categorized into two main families: C/D box small nucleolar RNAs (snoRNAs) and H/ACA snoRNAs, which are involved in specific methylations and pseudouridylations, respectively.
Small Nucleolar RNAs and Their Comprehensive Biological …
2022年8月26日 · Small nucleolar RNAs (snoRNAs) are a class of highly conserved, stable non-coding RNAs involved in both post-transcriptional modification of RNA and in ribosome biogenesis. Recent research shows that the dysfunction of snoRNAs plays a pivotal role in hepatocellular carcinoma (HCC) and related etiologies, such as hepatitis B virus (HBV ...
Exploring the expanding universe of small RNAs - Nature
2022年4月12日 · The world of small noncoding RNAs (sncRNAs) is ever-expanding, from small interfering RNA, microRNA and Piwi-interacting RNA to the recently emerging non-canonical sncRNAs derived from...
The Emerging Landscape of Small Nucleolar RNAs in Cell Biology
Small nucleolar RNAs (snoRNAs) are a large class of small noncoding RNAs present in all eukaryotes sequenced thus far. As a family, they have been well characterized as playing a central role in ribosome biogenesis, guiding either the sequence-specific chemical modification of pre-rRNA (ribosomal RNA) or its processing.