2025年1月24日 · Drug discovery is the process through which potential new medicines are identified. It involves a wide range of scientific disciplines, including biology, chemistry and pharmacology.

2010年12月2日 · Nature Reviews Drug Discovery is a journal for people interested in drug discovery and development. It features reviews, news, analysis and research highlights.

2022年5月30日 · Phenotypic drug discovery has re-emerged over the past decade as an approach to systematically pursue drug discovery based on therapeutic effects in realistic disease models.

2025年1月22日 · Drug discovery and development articles from across Nature Portfolio Drug discovery and development together are the complete process of identifying a new drug and bringing it to market.

2024年11月21日 · The ingestible device shoots out tiny jets of drugs to deliver them to the GI tract of pigs and dogs — plus how light-powered catalysts could help break down ‘forever chemicals’.

2011年6月24日 · In our analysis, we found that there are numerous diverse MMOAs for approved new first-in-class drugs, but drug discovery at present appears to be dominated by a 'one size fits all' approach, in ...

2024年1月2日 · The FDA continues to flesh out its use of regulatory flexibility in neurology, approving several new drugs on the basis of surrogate biomarkers, inconclusive evidence of clinically significant ...

Drug discovery and development is notoriously sluggish. Now, big data and AI promise to make some steps in the pipeline up to ten times faster.

2024年11月7日 · The rapid expansion of drug target structures in both the Protein Data Bank and AlphaFold database, which has significantly increased opportunities for discovering new drugs.

2021年1月28日 · Here, we summarize recent technological developments that are enabling natural product-based drug discovery, highlight selected applications and discuss key opportunities.