inhibin, hormone secreted by the granulosa cells in the ovaries of women that acts primarily to inhibit the secretion of follicle-stimulating hormone by the anterior pituitary gland.

Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. Identified in 1986, [1][2] activin enhances FSH biosynthesis and secretion, and participates in the regulation of the menstrual cycle.

2005年3月1日 · Inhibins are glycoproteins produced by the granulosa and theca cells of the ovary and by the Sertoli cells of the testis. They are of great importance for the negative feedback control of pituitary gonadotrophin secretion.

2014年10月1日 · On the occasion of the 90th birthday of inhibin, we review its structure and its biology within and beyond the reproductive tract, illustrating the critical role of this powerful gonadal hormone in reproduction and, therefore, life itself.

Inhibin was first identified as a gonadal hormone that potently inhibits pituitary follicle-stimu- lating hormone (FSH) synthesis and secretion. Although the notion of a nonsteroidal, gonadally derived inhibitory substance was realized in the early 1930s (McCullagh, 1932) identification of the.

Inhibin is a hormone produced primarily by the gonads, specifically the Sertoli cells in males and the granulosa cells in females, that plays a crucial role in regulating reproductive processes. It functions mainly to inhibit the secretion of follicle-stimulating hormone (FSH) from the anterior pituitary gland, thereby providing feedback to the ...

Inhibin hormone is synthesize and secreted by granulosa and theca cells of ovary having glycoprotein in nature. Inhibin is effectively important for the control of reproductive functions in mammalians.

It is a hormone secreted in response to follicle-stimulating hormone (FSH). In turn, this hormone eventually suppresses the production and release of FSH from the pituitary gland.

Inhibin is a putative gonadal hormone that, in recent years, has established itself as a factor responsible for the control of FSH. Besides, certain dimmers of the β-subunit of inhibin are known to activate the release of FSH (44,77).

Inhibin is a glycoprotein hormone, consisting of two dissimilar, disulphide-linked subunits, termed α (MW 20kD) and β (MW 3-15kD), which inhibits the production and/or secretion of pituitary gonadotrophins, preferentially follicle stimulating hormone (FSH).