Down syndrome (United States) or Down's syndrome (United Kingdom and other English-speaking nations), also known as trisomy 21, is a genetic disorder caused by the presence of all or part of a third copy of 展开

The cause of the extra full or partial chromosome is still unknown. Most of the time, Down syndrome is caused by a random mistake in cell division during early development of the fetus, but not inherited, and there is no scientific research which shows … 展开

Efforts such as early childhood intervention, therapies, screening for common medical issues, a good family environment, and work-related training can improve the development … 展开

Those with Down syndrome nearly always have physical and intellectual disabilities. As adults, their mental abilities are typically similar to those of … 展开

The extra genetic material present in Down syndrome results in overexpression of a portion of the 310 genes located on chromosome 21. This … 展开

Screening before birth
Guidelines recommend screening for Down syndrome to be offered to all pregnant women, … 展开

Between 5–15% of children with Down syndrome in Sweden attend regular school. Some graduate from high school; however, most do not. Of … 展开