Cefminox - Wikipedia
Cefminox is a broad-spectrum, bactericidal cephalosporin antibiotic. It is especially effective against Gram-negative and anaerobic bacteria. [ citation needed ] The following represents MIC data for a few medically significant microorganisms.
Cefminox, a Dual Agonist of Prostacyclin Receptor and …
2018年2月23日 · As a dual agonist of IP and PPARγ, cefminox significantly inhibited growth of PASMCs through up-regulation of PTEN expression and cAMP production, and reversed remodeling of the pulmonary artery and RV in a rat HPH model. Cefminox, therefore, has potential as a novel treatment for PAH.
Cefminox sodium alleviates the high-fat high-sugar-fed mice's …
2023年11月7日 · The increasing global prevalence of nonalcoholic fatty liver disease (NAFLD) starves for effective therapy, but no agent has been approved yet. We sought to evaluate the therapy of cefminox sodium (CMNX) on fatty accumulation in animal and cell models and explore the underlying mechanisms.
Cefminox: Uses, Interactions, Mechanism of Action - DrugBank …
2015年5月11日 · The therapeutic efficacy of Urokinase can be decreased when used in combination with Cefminox. Cefminox may decrease the excretion rate of Vaborbactam which could result in a higher serum level. The risk or severity of nephrotoxicity can be increased when Valaciclovir is combined with Cefminox.
Cefminox, a Dual Agonist of Prostacyclin Receptor and …
2018年2月23日 · Our results identified cefminox as a dual agonist of IP and PPARγ that significantly inhibits PASMC proliferation by up-regulation of PTEN and cAMP, suggesting that it has potential for treatment of PAH.
Cefminox, a Dual Agonist of Prostacyclin Receptor and …
2018年2月22日 · Cefminox, a Dual Agonist of Prostacyclin Receptor and Peroxisome Proliferator-Activated Receptor-Gamma Identified by Virtual Screening, Has Therapeutic Efficacy against Hypoxia-Induced Pulmonary Hypertension in Rats.
Cefminox | C16H21N7O7S3 | CID 71141 - PubChem
Cefminox is a semisynthetic, second-generation, beta-lactamase-stable cephalosporin with antibacterial activity. Cefminox binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall.
Pharmacology of cefminox, a new bactericidal cephamycin
Cefminox is a new cephamycin antibiotic possessing a D-amino acid moiety derived from D-cysteine at the C-7B side chain. Cefminox is active against a wide range of bacteria, especially Gram-negative and anaerobic bacteria.
CEFMINOX SODIUM HEPTAHYDRATE - National Center for …
Cefminox is a broad-spectrum, bactericidal cephalosporin antibiotic. It is especially effective against Gram-negative and anaerobic bacteria. It is indicated in treatment of the following infections caused by sensitive bacteria: 1.
Blockade of Hepatocyte PCSK9 Ameliorates Hepatic Ischemia …
2023年9月16日 · (C) Detected mitophagy in H/R AML12 cells (pretreated by cefminox sodium ,10 μmol/L). In summary, our findings demonstrate that inhibition of PCSK9 promotes PINK1-Parkin–mediated mitochondrial autophagy, and this regulatory effect is mediated through the inhibition of PTEN.