The BRAF gene provides instructions to a protein responsible for managing important cell functions related to growth. If there is a mutation in the gene, it stops working correctly and signals cells to divide uncontrollably, which leads to a tumor. Doctors can collect and analyze a sample of the tumor or use blood tests to detect the BRAF mutation.

BRAF is a human gene that encodes a protein called B-Raf. The gene is also referred to as proto-oncogene B-Raf and v-Raf murine sarcoma viral oncogene homolog B, while the protein is more formally known as serine/threonine-protein kinase B-Raf. [5][6]

2024年12月24日 · BRAF (B-Raf Proto-Oncogene, Serine/Threonine Kinase) is a Protein Coding gene. Diseases associated with BRAF include Lung Cancer and Cardiofaciocutaneous Syndrome 1. Among its related pathways are IL-9 Signaling Pathways and Prolactin Signaling.

The BRAF gene encodes for a serine/threonine protein kinase that participates in the MAPK/ERK signalling pathway and plays a vital role in cancers and developmental syndromes (RASopathies). The current review discusses the clinical significance of ...

The BRAF gene provides instructions for making a protein that helps transmit chemical signals from outside the cell to the cell's nucleus. This protein is part of a signaling pathway known as the RAS/MAPK pathway, which controls several important cell functions.

2025年1月4日 · Gene ID: 673, updated on 4-Jan-2025. This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion.

BRAF (B-Raf proto-oncogene, serine/threonine kinase) is a gene that encodes the protein serine/threonine-protein kinase B-raf. BRAF is involved in many cellular processes, including cell proliferation, differentiation, and transcriptional regulation.

The BRAF gene, a serine-threonine kinase in the family of RAF kinases, is located on chromosome 7, and is mainly involved in transmitting signals from the extracellular space into the nucleus thereby regulating cell proliferation, differentiation, and migration through the mitogen activation protein kinase (MAPK) pathway. 25,26 There are more ...

BRAF (Gene) is a human proto-oncogene that encodes the B-Raf protein, playing a crucial role in growth signal transduction by regulating the MAPK/ERK signaling pathway. Mutations in BRAF, such as V600E, lead to uncontrolled cell proliferation and tumorigenesis, commonly found in various cancers including melanoma and certain brain tumors.

Gene mutations can induce cellular alteration and malignant transformation. Development of many types of cancer is associated with mutations in the B-raf proto-oncogene (BRAF) gene. The encoded protein is a component of the mitogen-activated protein kinases/extracellular signal-regulated kinases (MAPK/ERK) signaling pathway, transmitting ...