In organic chemistry, phosphonates or phosphonic acids are organophosphorus compounds containing C−PO (OR)2 groups, where R is an organic group (alkyl, aryl). If R is hydrogen then the compound is a dialkyl phosphite, which is a different functional group.

Triflic anhydride promotes a phosphorylation of ketones to provide vinylphosphorus compounds under solvent- and metal-free conditions. Both aryl and alkyl ketones give vinyl phosphonates in high to excellent yields. This convenient and mild reaction can easily be scaled up.

A metal-, toxic chloride reagent-free activating strategy of various phosphates with Tf 2 O and pyridine enables a facile synthesis of functional phosphates such as alkyl phosphates, aza phosphates, thiophosphate, and mixed diaryl phosphates via a …

Alkyl phosphates belong to a group of organic compounds called organophosphates. They are esters of phosphoric acid H 3 PO 4 and corresponding alcohol. For example, the formula of methyl phosphate is CH 3 -H 2 PO 4, dimethyl phosphate – (CH 3) 2 HPO 4 and trimethyl phosphate – (CH 3) 3 PO 4.

The reaction of a trialkyl phosphite with an alkyl halide to produce an alkyl phosphonate. The first step involves nucleophilic attack by the phosphorus on the alkyl halide, followed by the halide ion dealkylation of the resulting trialkoxyphosphonium salt.

2024年3月15日 · During the calculation of ideal gas thermodynamic properties, we found that the rotational barriers of methyl tops bound to oxygen or phosphorus were noticeably lower than those common in alkyl chains.

2023年8月8日 · Herein, we report the phosphonylation of a diverse range of alkyl radicals with benzhydryl-catechol-phosphite (BecaP), which incorporates a phosphoranyl radical-stabilizing catechol ligand and a benzhydryl (Bzh) radical-leaving group (Scheme 1C).

2022年11月2日 · This is the first case that a series of dialkyl and alkyl, alkyl’ alkylphosphonates were prepared from the corresponding alkylphosphonic acid, by a 2-step method in a pure form.

Constructing organic fluorophosphines, vital drug skeletons, through the direct uorination of readily available alkyl phosphonates has been impeded fl due to the intrinsic low electrophilicity of...

2015年4月29日 · Three novel 2-alkyl-2-oxo-1,3,2-dioxaphospholanes, cyclic monomers for the ring-opening polymerization (ROP) toward poly(alkyl alkylene phosphonate)s, were synthesized by robust two- or three-step protocols in reasonable yields and high purity.