Introduction Colonisation with Pseudomonas aeruginosa is a complication of bronchiectasis and chronic bronchitis and is associated with more severe disease and lower quality of life. Colomycin ...

Sputum induction (SI) by inhalation of nebulised hypertonic saline is an efficient and non-invasive way of obtaining samples to assess airway inflammation and diagnose pulmonary infections such as ...

Background It is current practice to use a single diagnostic sleep study in the diagnostic workup of obstructive sleep apnoea (OSA). However, a relevant night-to-night variability (NtNV) of ...

Statins reduce cholesterol levels by inhibiting 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase and have an established role in the treatment of atherosclerotic disease. Recent research has ...

Analysis of airflow in the terminal portion of the maximal expiratory flow volume curve has been suggested as a useful test for the early diagnosis of chronic airways obstruction. Whether such an ...

Pulmonary rehabilitation has established itself as a vital and core therapy for people with chronic lung disease. Significant improvements are seen in several patient outcomes, for the thousands ...

We present the case of a 45-year-old man who reported 2 years of cough and expectoration and 1 year of dyspnoea. He had a history of dry nasal snuff inhalation 15 times/day for 10 years, worked as a ...

Cook and Strachan are to be congratulated on their series of meta-analyses on the health effects of passive smoking. However, in their analysis of parental smoking and spirometric indices they gave as ...

Cyclo-oxygenase (COX), also known as prostaglandin H synthase (PGHS), is the rate limiting enzyme for the conversion of arachidonic acid to prostanoids and exists in two isoforms. COX-1 is ...

Background This study aimed to evaluate whether incidental CT findings of emphysema, airway thickening and bronchiectasis, as seen on CT scans performed for other non-pulmonary clinical indications, ...

Background: A study was undertaken to evaluate exacerbations and their impact on the health related quality of life (HRQL) of patients with chronic obstructive pulmonary disease (COPD). Methods: A 2 ...

Background: A study was undertaken to assess the prevalence of reported respiratory symptoms in a population aged over 75 years and their association with mortality. Methods: A total of 14 458 people ...