Introduction Colonisation with Pseudomonas aeruginosa is a complication of bronchiectasis and chronic bronchitis and is associated with more severe disease and lower quality of life. Colomycin ...

Background The integration of artificial intelligence (AI) into critical care offers significant potential to enhance early diagnosis, predict patient deterioration, personalise treatment and inform ...

Introduction Fibroblastic foci represent the cardinal pathogenic lesion in idiopathic pulmonary fibrosis (IPF) and comprise activated fibroblasts and myofibroblasts, the key effector cells responsible ...

Introduction Cardiopulmonary exercise testing (CPET) is shown to be feasible in patients with interstitial lung disease (ILD), highlighting its prospective use as an outcome measure for prognostic ...

### Steering group Julia Bott (Chair), support to Section 6, Consultant Physiotherapist, Surrey PCT NW Locality Sheric Ellum, support to Section 5, Consultant Physiotherapist, Guy's & St Thomas' NHS ...

### Philosophy of the guideline ### Assessing patients Figure 1 Chart 1: Oxygen prescription for acutely hypoxaemic patients in hospital. ABG, arterial blood gas; COPD, chronic obstructive pulmonary ...

A pillar of the WHO End TB Strategy is targeted latent tuberculosis infection (LTBI) testing to identify persons who would benefit from TB preventive treatment (TPT).1 The WHO recommends the ...

Background: Timeliness is an important dimension of health care quality. It is unclear whether timeliness improves clinical outcomes in patients with lung cancer. Methods: This study systematically ...

Rationale Progressive lung function (LF) decline in patients with asthma contributes to worse outcomes. Asthma exacerbations are thought to contribute to this decline; however, evidence is limited ...

Background Lung cancer is associated with poor health-related quality of life (HRQoL) and high symptom burden. This trial aimed to assess the efficacy of home-based rehabilitation versus usual care in ...

Background In the classic model of obstructive sleep apnoea (OSA), respiratory events occur with sleep-related dilator muscle hypotonia, precipitating increased neural ventilatory ‘drive’. By contrast ...

Results In a cohort of 493 IPF patients, the survival of patients with a high NLR was significantly lower than in those with a low NLR (median survival 36 months vs 62 months; Hazard Ratio (HR) 1.7, ...