This study shows that engineered E. coli Nissle 1917 producing indole-3-acetic acid (IAA), an AhR agonist, modulate the tumor ...

Basophils trigger a cytokine cascade that improves antitumor immunity in mice, offering potential targets for cancer ...

From the approval of the first immune checkpoint inhibitors to the development of chimeric antigen receptor T cells, immunotherapy has demonstrated ...

However, 25-hydroxycholesterol prevents this inhibition, and therefore enables better activation of anti-tumor immunity. Prof. Hugues' team then deleted this enzyme in mouse lymphatic endothelial ...

In a nutshell Aspirin may help prevent cancer from spreading by stopping platelets from producing thromboxane A2 (TXA2), ...

A new review article published in Genes & Diseases sheds light on the complex molecular mechanisms through which ...

Clinical research has long focused on ways to harness the actions of the immune system. From vaccines to immunotherapies, ...

Additional Phase 2 data for vilastobart,a tumor-activated, Fc-enhanced anti-CTLA-4, in combination with atezolizumab in patients with MSS CRC ...

Pancreatic cancer that spreads to the liver is especially difficult to treat because the liver naturally suppresses immune ...

ELF4, a transcription factor belonging to the ETS family, has emerged as a pivotal regulator in cell differentiation, immune system function, and cancer progression. This newly published review ...