B-cell acute lymphoblastic leukemia (B-ALL) is a life-threatening and highly aggressive form of blood cancer. It is the most ...

Everything came together last year when Alexander Marson, Gurumurthy, and colleagues used Easi-CRISPR to reprogram the structure and function of human T cells without the need for viral vectors 6.

For successful cell division, chromosomal DNA needs to be packed into compact rod-shaped structures. Defects in this process can lead to cell death or diseases like cancer. A new study has shown how ...

The high determinant density model, in which the structure of the allogeneic MHC molecule governs T-cell recognition; [34] The multiple binary complex model, in which alloantigen recognition is ...

Some of the body's cells stay put for life ... "Until now, it hasn't really been possible to visualize their internal structure in any significant detail," says lab head Gregory M.

It develops from the abnormal multiplication of T cells, or T-lymphocytes, a type of white blood cell essential for immune system function. The specific treatment course and prognosis for T-cell ...

It's also critical to understand that the specific sequence of A, T, C ... within a particular cell, but within the organism as a whole. Beyond the ladder-like structure described above, another ...