C&EN1 个月
OpenMMDL - Simplifying the Complex: Building, Simulating, and Analyzing Protein–Ligand ...
Department of Biology, Chemistry and Pharmacy, Institute of Pharmacy, Molecular Design Group, Königin-Luisestr. 2 + 4, 14195 Berlin, Germany Department of Biology, Chemistry and Pharmacy, Institute of ...
C&EN1 个月
Stereoselective Synthesis of Highly Functionalized Bicyclo[2.1.0]pentanes by Sequential [2 ...
Department of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, Georgia 30322, United States ...
Frontiers1 年
Overexpression of plastid lipid-associated protein in marine diatom enhances the ...
Transcriptomic analysis revealed that PAP expression and the morphological changes altered xanthophyll synthesis and storage, which affected the assembly of the fucoxanthin chlorophyll a/c-binding ...
Frontiers3 年
Arginine and Arginine-Rich Peptides as Modulators of Protein Aggregation and Cytotoxicity ...
While monomeric arginine is well-established as an inhibitor of protein aggregation in solution, no studies have comprehensively discussed the anti-aggregatory properties of arginine and CARPs on ...
eLife4 年
Structure of dual BON-domain protein DolP identifies phospholipid binding as a new ...
Some virulence factors serve to maintain the integrity of the outer membrane, including DolP (formerly YraP) a protein of unresolved structure and function. Here, we reveal DolP is a lipoprotein ...
eLife5 年
De novo design of a homo-trimeric amantadine-binding protein
The computational design of a symmetric protein homo-oligomer that binds a symmetry-matched small molecule larger than a metal ion has not yet been achieved. We used de novo protein design to create a ...