An effective HIV-1 vaccine must therefore elicit antibodies that can neutralize many variants of the virus. While broadly neutralizing antibodies (bnAbs) have been isolated from HIV-1 infected ...

但希望之光已然显现：研究者通过腺相关病毒（AAV）基因治疗，将衰老小鼠脑血管的糖萼厚度恢复83%，不仅逆转血管渗漏，更让20月龄老年鼠在迷宫测试中展现超越年轻组的空间记忆能力。这项颠覆性发现不仅重新定义了血脑屏障的防御机制，更为对抗阿尔茨海默病开辟了全新治疗维度：修复纳米级的糖萼结构，或将成为阻止大脑"塌方式衰老"的关键突破口。

Bottlebrush Barrier. The glycocalyx layer (purple, left) that coats brain blood vessels consists of numerous glycoproteins, ...

Researchers reveal that the loss of mucin-type O-glycosylation in the brain endothelial glycocalyx weakens the blood-brain ...

Laboratory of Fruit Quality Biology, The State Agriculture Ministry Laboratory of Horticultural Plant Growth, Development and Quality Improvement, Zhejiang Provincial Key Laboratory of Integrative ...

“Glycosylation can affect how cells attach to each other (adhesion), how they move ... where the presence of different sugar groups on proteins in red blood cells determines blood type (A, B, O, and ...

"Glycosylation can affect how cells attach to ... groups on proteins in red blood cells determines blood type (A, B, O, and AB). This plays a major role in deciding the success of blood ...

"Glycosylation can affect how cells attach to ... groups on proteins in red blood cells determines blood type (A, B, O, and AB). This plays a major role in deciding the success of blood ...

“Glycosylation can affect how cells attach to each other (adhesion), how they move ... where the presence of different sugar groups on proteins in red blood cells determines blood type (A, B, O, and ...

“Glycosylation can affect how cells attach to ... groups on proteins in red blood cells determines blood type (A, B, O, and AB). This plays a major role in deciding the success of blood ...

Based on these insights, hypoxia is a major driving force of the energetic reprograming of cancer cells, largely affecting glycosylation in a HIF-1α-dependent manner. As such, both O-GlcNAc ...

Glycosylation was previously considered to be restricted to eukaryotes; however, through advances in analytical methods and genome sequencing, there have been increasing reports of both O-linked ...