NMR is used in chemistry and related fields for high-resolution molecular structure determination and the study of molecular dynamics. Scientists find that spongin, a key biomaterial in sponges ...
Thomas Lord Department of Mechanical Engineering and Materials Science, Duke University, Durham, North Carolina 27708, United States Department of Chemistry, Duke University, Durham, North Carolina ...
Three-dimensional representation of the Quipu superstructure. Credit: MPE “If you look at the distribution of the galaxy clusters in the sky in a spherical shell with a distance of 416 to 826 million ...
RNA has recently gained attention as a promising drug target. Unfortunately, only a small fraction of RNA structures have been determined experimentally, and the process of uncovering these ...
Department of Chemistry, King’s College London, London SE1 1DB, United Kingdom Biological Physics and Soft Matter Group, Department of Physics, King’s College London, London WC2R 2LS, United Kingdom ...
The second stage of the NMR structure determination process involves assignment of the side chain resonances and collection of structural data, including interproton distance restraints from ...
Efficacy of all four of our candidate inhibitors in reducing cell seeding by MSA-derived α-syn fibrils shows the clinical relevance of our design. Further, in the NMR structure of full-length α-syn ...
Single-structure models derived from X-ray data do not adequately account for the inherent, functionally important dynamics of protein molecules. We generated ensembles of structures by time-averaged ...