NADH, also known as nicotinamide adenine dinucleotide, is a crucial coenzyme present in every cell of our bodies, serving as an elemental source for energy production. It aids in turning the food ...

College of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, P. R. China ...

Physical inactivity, excess energy consumption, and obesity are associated with elevated systemic oxidative stress and the sustained activation of redox-sensitive stress-activated protein kinase (SAPK ...

NADH:ubiquinone oxidoreductase subunit B4; NF-κB, nuclear factor kappa B; NIX, Nip3-like protein X; Nthl1, Nth like DNA glycosylase 1; OPA1, optic atrophy 1 protein; OPTN, optineurin; PD, Parkinson’s ...

Metabolomics refers to the systematic identification and quantification of the small molecule metabolic products (the metabolome) of a biological system (cell, tissue, organ, biological fluid, or ...

Understanding the molecular mechanisms of insulin resistance remains a major medical challenge of the twenty-first century. Over the last half-century, many hypotheses have been proposed to ...

This cover highlights the article Multimodal mechanisms of human centriole engagement and disengagement by Kei K. Ito, Shoji Hata, Daiju Kitagawa and colleagues. The cover image depicts the centriole ...

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This paper presents the important finding that BNIP3/NIX, a mitophagy receptor, and its binding to ATG18 are required for mitophagy during muscle cell reorganization in Drosophila. Although the ...

Centre for Sustainable Future Technologies, Fondazione Istituto Italiano di Tecnologia, Via Livorno 60, 10144 Turin, Italy Department of Applied Science and Technology, Politecnico di Torino, Corso ...

Objective Alcoholic liver disease (ALD) is a leading cause of death among chronic liver diseases. However, its pathogenesis has not been completely established. MicroRNAs (miRNAs) are key contributors ...

Similarly, mTOR (mechanistic target of rapamycin), a nutrient-sensing kinase, integrates signals related to growth and energy status to ... 16 CR achieves this by reducing NADH, an inhibitor of ...