A team of scientists at the Indiana University School of Medicine has identified that an eye condition affecting the retina, the light-sensing tissue in the back of the eye, may serve as an early ...

A retinal scan of a young mouse genetically predisposed to diabetes and obesity. Over time, the retina undergoes changes consistent with diabetic retinopathy, a condition where blood vessels swell ...

Collectively, our findings support that T cells accumulate during early AMD prior to degeneration in our mouse model, and that these cellular populations are associated to the RPE. Taken together, our ...

One of the most significant discoveries in the study was the identification of two mouse strains that closely resemble human retinal diseases. By performing eye exams—like what a human would ...

Genetic and protein analyses predict eye diseases One of the most significant discoveries in the study was the identification of two mouse strains that closely resemble human retinal diseases.

Four different assays were performed to identify NRL interactors. Affinity purifications with Glutathione and NRL antibodies were performed from bovine and mouse retinal lysates and subjected to mass ...

"Our study demonstrates that retinal dysfunction occurs in the APOE4 mouse model, mirroring aspects of Alzheimer's pathology," Abhyankar said. "These results underscore the potential of retinal ...

If you experience any of the symptoms of a retinal detachment, seek medical attention immediately. Time is of the essence in the treatment of a retinal detachment. Early treatment can improve the ...

Prior research using Aipl1-deficient mouse models and human retinal organoids demonstrated partial restoration of photoreceptor function through gene therapy. Four children aged 1.0 to 2.8 years ...

Retinal ganglion cells (RGCs) are the bridging neurons that connect the retinal input to the visual processing centres within the central nervous system. There is a remarkable diversity of RGCs and ...

The development of retinoschisis mouse models have provided a model system that closely resembles the human disease. Recent reports of RS1 gene transfer to these models and the sustained restoration ...