Polyphosphate (polyP) exists in all life forms; however, its biological functions in metazoans are understudied. Here, we explored Drosophila as the first genetic model to explore polyP biology in ...

Mitochondria are versatile organelles and essential components of numerous biological processes such as energy metabolism, signal transduction, and cell fate determination. In recent years, their ...

Imbalances in endoplasmic reticulum function and mitochondrial quality control are important potential drivers of inflammation and oxidative stress. In addition, many studies have confirmed the ...

She said red light therapy improves the functioning of the mitochondria, or the parts of cells that produce energy, which she hopes will increase her energy levels. In a 2024 study published in ...

2025 年 2 月 20 日，中国科学技术大学生命科学与医学部单革教授团队在 Circulation 在线发表题为“ Fast Degradation of MecciRNAs by SUPV3L1/ELAC2 Provides a Novel Opportunity to Tackle Heart Failure with Exogenous MecciRNA ” 的研究论文 ...

MecciRNA degradation complex and mecciRNAs interact with mitochondrial permeability transition pore and its regulators including TRAP1 (TNF receptor–associated protein 1) and CypD (cyclophilin D).

Scale bars = 500 nm. (E and F) Changes in myocardial mitochondrial complex II and IV enzyme activities in hearts (n=7). (G) The ATP content in myocardial tissue was measured by colorimetry (n=7). (H ...