Increased oxidative stress caused by mitochondrial degeneration has been reported in PD and ALS. The finding that mitochondrial toxins such as 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and ...

MecciRNA degradation complex and mecciRNAs interact with mitochondrial permeability transition pore and its regulators including TRAP1 (TNF receptor–associated protein 1) and CypD (cyclophilin D).

Scale bars = 500 nm. (E and F) Changes in myocardial mitochondrial complex II and IV enzyme activities in hearts (n=7). (G) The ATP content in myocardial tissue was measured by colorimetry (n=7). (H ...

Acute lung injury(ALI)/acute respiratory distress syndrome(ARDS) is a form of acute-onset hypoxemic respiratory failure characterised by an acute, diffuse ...

Cheng et al. identify a mitochondrial complex IV (CIV) deficiency in the brains of patients with sporadic amyotrophic lateral sclerosis (ALS). They demonstrate that defects in mitochondrial CIV ...

引言为何多数癌症患者对免疫治疗无反应？为何肿瘤总能在免疫系统的围剿中逃之夭夭？3月19日《Nature》杂志最新发表的研究“VDAC2 loss elicits tumour destruction and inflammation for ...

Prince Frederik of Luxembourg died on Feb. 28 from a rare mitochondrial disease, according to a statement issued over the weekend by his parents, Prince Robert and Princess Julie. He was 22.

Prince Frederik of Luxembourg has died at the age of 22 from POLG mitochondrial disease, a rare genetic disorder that he was born with, his family announced. Frederik de Nassau died in Paris on ...

Prince Frederik of Luxembourg, son of Prince Robert and Princess Julie of Nassau, passed away at 22 in Paris due to POLG mitochondrial disease. Diagnosed at 14, Frederik advocated for research and ...