The human body is estimated to remove 1% of its body mass, likely more than 200 billion cells, every day. To achieve this, we rely on a highly evolutionarily conserved process: apoptotic cell ...

In newborns, macrophages perform a process called efferocytosis, which recognizes and eats dying cells. This process triggers the production of a bioactive lipid called thromboxane, signaling ...

Further analysis through RNA sequencing revealed significant changes in macrophage gene expression, particularly related to autophagy and efferocytosis, which are essential for plaque stability.