Microglia are brain-resident macrophages playing pivotal roles in CNS development and homeostasis. Yet, the cellular and molecular basis governing microglia maintenance ...

Topline data from Phase 3 EFZO-FIT™ study of efzofitimod in pulmonary sarcoidosis expected in the third quarter of 2025.Fourth positive DSMB ...

For liver tissue, we analysed X-gal and BrdU labelling in two or three separate lobes for each animal (in total, 30–40 random areas of the sections from 2–3 liver lobes; 2,000 nuclei from each ...

Inhibiting this signal induces tumor regressions by triggering progenitor-to-hepatocyte differentiation, the same cell fate-switch that Notch controls during development. Transcriptomic analysis ...

Accumulation of calcium in the mitochondria of rat liver parenchymal cells at 16 and 24 hours after poisoning with carbon tetrachloride is associated with an increase in amount of liver inorganic ...

The vascular endothelial microenvironment, centered on vascular endothelial cells (VECs), includes the extracellular matrix and various vascular physicochemical factors. The VECs interact with ...

Acute and chronic liver injury models were performed in wild type and Trem-2-/-mice. Primary liver cells from both genotypes of mice were isolated for in vitro experiments. Results TREM-2 was ...

Aloe vera parenchyma offers a naturally structured, edible, and biodegradable alternative. The byproduct’s neutral taste, texture, and fibrous composition make it particularly appealing for cultivated ...