敲低 Parkin 后，检测 PFV Gag 过表达细胞中线粒体蛋白 Cox4 和 Tom20 的水平，发现 Cox4 和 Tom20 的减少得到逆转，同时 LC3 和 Tom20 的共定位也减少。这些结果表明，PFV Gag 诱导的 mitophagy 依赖于 Parkin。

免疫应答中，白细胞整合素 lfa1对淋巴细胞运输和黏附至关重要，但其激活后在细胞接触表面聚集的调控机制不明。研究人员探究自噬成分 lc3 与 lfa1运输的关系，发现 lc3 可调节 lfa1在接触表面的积累和淋巴细胞黏附，拓展了对淋巴细胞调控的认知。

In part 5, Dr. Hegde discusses how Limestone Calcined Clay Cement (LC3) can drive decarbonisation in construction by showcasing its carbon reduction potential, appealing to real estate developers and ...

Setting Standards for Long-Term Use of LC3. Finally, adopting LC3 on a wider scale will require updating building codes and construction standards to recognise its long-term durability. Government ...

The LC3-Skifter is a unique item needed to unlock one of the more useful abilities in Star Wars Outlaws. The LC3-Skifter can only be found in one place, so the ...

Autophagy was found to be perturbed in Parkin-Q311X mice at 16 to 17 months of age (Siddiqui et al., 2015). The number of LC3 puncta in the SNpc was increased in mutant versus wild-type control mice, ...

Objective To investigate the effect of adipocytokine Apelin-13 (AP13) on mitochondrial autophagy in myocardial ischemia reperfusion injury (MIRI) and its mechanism. Methods MIRI model was established ...

非泛素化依赖通路主要由自噬受体介导，它们不经泛素化直接与LC3结合，从而启动线粒体自噬。FUNDC1可通过与LC3相互作用诱导低氧下哺乳动物细胞的线粒体自噬。FUNDC1介导的线粒体自噬不依赖于Parkin，… ...

The LC3 formula is 50% clinker, 30% calcined clay, 15% limestone and 5% gypsum. Portland cement is about 91% clinker, while portland limestone cement (PLC) ...

Parkin orchestrates mitophagy by coordinating mitochondrial lipid remodeling and sequential production of mitochondrial phosphatic acid and diacylglycerol.image EMBO Press is an editorially ...