As well as mammalian cells, many different pathogens, including viruses, bacteria, fungi and parasites, also use glycoproteins extensively for diverse functions, in part similar to eukaryotic cells.

Bottlebrush Barrier. The glycocalyx layer (purple, left) that coats brain blood vessels consists of numerous glycoproteins, ...

The immune system responds to an infection by producing antibodies that recognize and bind to the cell surface of the ...

In the wake of advances in the production and crystallization of glycoproteins, we believe there should now be a wider discussion about the application and control of refinement standards applied ...

Researchers reveal that the loss of mucin-type O-glycosylation in the brain endothelial glycocalyx weakens the blood-brain ...

Antigenic variation is a key mechanism by which pathogens evade the immune system. New research has shown how trypanosomes change their antigen expression.

More information: Self-regulation of MGAT4A and MGAT4B activity toward glycoproteins through interaction of lectin domain with their own N-glycans, iScience (2024). DOI: 10.1016/j.isci.2024.111066 ...

Protein glycosylation, which creates glycoproteins, is common and influences cell adhesion, signaling, protein folding, and ...