A recent study has revealed how Epstein-Barr virus (EBV) intensifies ulcerative colitis (UC), a debilitating inflammatory ...

A recent study has revealed how Epstein-Barr virus (EBV) intensifies ulcerative colitis (UC), a debilitating inflammatory ...

A new study reveals that Epstein-Barr virus (EBV) infection exacerbates ulcerative colitis (UC) by driving macrophage pyroptosis through the upregulation of glycolysis. This finding provides a ...

The study, published in Precision Clinical Medicine, demonstrates that EBV infection activates pyroptosis—a form of programmed cell death—in intestinal macrophages by upregulating glycolysis. This ...

We also provide an overview of experimental guidelines on how to assess metabolism at the cellular level using Seahorse-based bioenergetic analysis including a review of pharmacologic agents used to ...

A recent study has revealed how Epstein-Barr virus (EBV) intensifies ulcerative colitis (UC), a debilitating inflammatory bowel disease. Researchers ...

Ulcerative colitis (UC) is a chronic, relapsing disease that causes painful inflammation and ulcers in the colon.

In contrast, M1 macrophages rely on aerobic glycolysis to lactate (2 ATP/glucose) for energy generation (211). Aerobic glycolysis is also known as Warburg metabolism and this phenotype has also been ...

Colorectal cancer (CRC) is the third most common malignancy and the second leading cause of cancer-related deaths worldwide.

glycolysis, and lysosomal activity, allowing the team to pinpoint how bacterial remnants influence cell metabolism. The study found that macrophages do not merely discard bacterial debris after ...