DNA in the nucleus of mammalian cells is extensively associated with proteins. Potential anticancer agents can access, recognize and alkylate nucleosomal DNA, even at sites that seem completely ...

Gene relation prediction is crucial for understanding cancer pathways and developing targeted treatments. This study proposes a novel Graph Transformer Network to predict gene relations by integrating ...

Protein−DNA interactions are essential for gene maintenance, replication, and expression. Characterizing how proteins interact with and change the structure of DNA is crucial in elucidating the ...

Nanopores are under development for the detection of a variety of analytes and the investigation of chemical reactions at the single molecule level. In particular, the analysis of nucleic acid ...

A century later, scientists accelerated the search for proteins by working out how our bodies make them. Each protein is encoded by a gene in our DNA. To make a protein, our cells make a copy of ...

Research Article Published: September 1999 Rapid identification of DNA-binding proteins by mass spectrometry Eckhard Nordhoff, Anne-M. Krogsdam, Helle F. Jørgensen, Birgitte H. Kallipolitis ...

The classification of DNA-binding proteins (DBPs) and RNA-binding proteins (RBPs) is essential for understanding molecular interactions and regulatory functions. However, the existing computational ...