ERRα 促进 PCSCs 向 OXPHOS 的能量代谢转变:利用 Seahorse Extracellular Flux 分析仪检测发现,PCSCs 富集的前列腺球体相对于其贴壁亲本细胞,具有更高的氧消耗率(OCR)和 ATP 产生,同时细胞外酸化率(ECAR)降低,表明 PCSCs 更依赖 OXPHOS 供能。此外,ERRα 过表达增强了 ...
线粒体是通过三羧酸(TCA)循环和氧化磷酸化(OXPHOS)参与能量代谢的重要细胞器 ,NK细胞的代谢恢复能力与其效应功能密切相关,可受细胞因子 ...
This cover highlights the article Multimodal mechanisms of human centriole engagement and disengagement by Kei K. Ito, Shoji Hata, Daiju Kitagawa and colleagues. The cover image depicts the centriole ...
Investopedia contributors come from a range of backgrounds, and over 25 years there have been thousands of expert writers and editors who have contributed. Theresa Chiechi / Investopedia A cease ...
Keep the champagne and your ballot of predictions handy, because it's Oscars time. The 97th annual Academy Awards are coming to a television, smartphone, and streaming setup near you tonight ...
Louis, St. Louis, MO, United States Although estrogen-related receptor α (ERRα) holds significant therapeutic potential for treating various disorders, developing selective agonists remains ...
Processes such as mitochondrial fission, fusion, mitophagy, changes in membrane potential, reactive oxygen species (ROS) accumulation, and oxidative phosphorylation (OXPHOS) are all linked to drug ...
Dizziness and nausea are two symptoms that often happen at the same time and aren't usually serious. The symptoms may be due to benign paroxysmal positional vertigo, pregnancy, or motion sickness, for ...
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