IN the nucleic acids, cytosine is connected to a sugar residue through N 1 of the pyrimidine ring. Here we describe the results of an X-ray diffraction analysis of crystals of N 1-methyl cytosine.

With the arrival of a new class of single-nucleotide editors, researchers can target the most common type of pathogenic SNP in humans. Now, researchers at Harvard University have designed a new class ...

Methylation as a Cancer Switch Courtesy of Richard Roberts, New England BiolabsReaction model: Methyltransferase (white) is methylating cyclic carbon 5 of a cytosine nucleotide. The tenuous link ...