CRISPR-based screening identifies H2AZ1 as a driver of cellular senescence. (A) Schematic of CRISPR-based loss-of-function ...

A recent study involving researchers from the University of Basel reveals that slowing down the intracellular transport of ...

A recent study involving researchers from the University of Basel reveals that slowing down the intracellular transport of ...

Single-cell CRISPR screening is a powerful method for biological discovery. Such screens genetically perturb many genes in parallel and use single-cell RNA sequencing to assess the transcriptomic ...

For decades, researchers have wondered why some people with risky gene variants go on to develop Parkinson’s disease, while ...

Scientists discovered a cancer-fighting compound in mold from ancient tombs, revealing a powerful new drug against leukemia.

CRISPR screens are untangling molecular mechanisms that drive biological processes with greater precision and detail. Lei Tang; Comments & Opinion 06 Dec 2024 Nature Methods. Volume: 21, P: 2226.

They also found that after the extra chromosome was removed, genes tied to nervous system development were more active and ...