car-nk 细胞升级： 在靶向 bcma 的 car-nk 细胞中敲除 ube2f ，其对耐药 白血病细胞的杀伤效率在第 3 轮挑战中仍维持初始水平，ifn-γ 分泌量增加 3 倍。

CRISPR-Cas systems, widely regarded as one of the most revolutionary genome editing tools, ... (NK) cells as vehicles for CAR engineering. Katy Rezvani, ...

Ryotaro Hashizume and colleagues from Mie University in Japan report that it is possible to cut away the surplus chromosome in affected cells, which appears to bring their behavior closer to typical ...

CRISPR-edited stem cells reveal hidden causes of autism. ScienceDaily. Retrieved June 14, 2025 from www.sciencedaily.com / releases / 2025 / 06 / 250614034240.htm. Kobe University.

A ternary dispersion solvent system─comprising water, 1-propanol, and cyclohexanol─was investigated for the fabrication of membrane electrode assemblies (MEAs) via screen printing in proton exchange ...

不过好消息是，科学家们已经找到了办法来解决这个问题。 说白了，研究人员利用crispr-cas9技术成功敲除了crem基因，并且观察到了令人振奋的结果：没有了crem的阻碍，car-nk细胞不仅能够更有效地识别并摧毁癌细胞，还能抵抗住肿瘤微环境中的免疫抑制因素。

Vienna, Austria – June 6, 2025 — Myllia Biotechnology, a pioneer in functional genomics in primary human cells, today announced a major technological breakthrough with the launch of VISTA™—the first ...

More information: Sophia M. Lamperis et al, CRISPR screen reveals a simultaneous targeted mechanism to reduce cancer cell selenium and increase lipid oxidation to induce ferroptosis, Proceedings ...

CRISPR-Cas9 gene editing in blood stem cells, especially with AAV6 vectors, induces DNA damage responses and inflammatory pathways, leading to senescence-like states that impair long-term ...

Epididymal NK/T cell lymphoma is sporadic among non-nasal type extranodal NK/T cell lymphomas, with only one documented case involving the epididymis reported to date. DU W et al. described a case in ...

Summary:. Though NK cells often infiltrate the breast tumor microenvironment, they are frequently described as dysfunctional in this setting, and mechanisms limiting their antitumor cytotoxic ...