In this study, we developed a novel diagnostic tool targeting the speB gene of GAS, designated GAS-MCDA-CRISPR, for the simple, rapid, and sensitive diagnosis of GAS infections. The detection platform ...

To gain a better understanding of its anti-tumor mechanism, we perform a temporally resolved CRISPR-Cas9 screen to identify factors governing the DAC response. We show that DNA damage generated by ...

This month's cover highlights the article Immune cells adapt to confined environments in vivo to optimise nuclear plasticity for migration by Helen Weavers and Tua Karling. The cover features confocal ...

The root of their malaise was a genetic experiment. When the monkeys were single-celled embryos, scientists had used CRISPR editing tools to silence, or “knock out”, a gene that helps regulate ...

然而，目前还没有能够以通用的方式实现对未经修饰的内源性 RNA 进行单分子活细胞成像。 2025年2月18日，诺贝尔化学奖得主、CRISPR 基因编辑技术先驱 Jennifer Doudna 教授团队在 Nature Biotechnology 期刊发表了题为：Single-molecule live-cell RNA imaging with CRISPR–Csm 的研究论文。

The first gene therapy utilizing CRISPR/Cas9 technology has received approval for clinical use, offering a groundbreaking treatment option for patients suffering from ?-thalassemia and sickle cell ...

More information: Ryotaro Hashizume et al, Trisomic rescue via allele-specific multiple chromosome cleavage using CRISPR-Cas9 in trisomy 21 cells, PNAS Nexus (2025). DOI: 10.1093/pnasnexus/pgaf022 ...

CRISPR Therapeutics AG (NASDAQ:CRSP) rose for a fourth day on Friday, ending the day higher by 14.33 percent to finish at $49.72 apiece, as investors cheered its upgraded rating from an investment ...

Evercore ISI has upgraded CRISPR Therapeutics (NASDAQ:CRSP) to outperform from in line, citing upcoming catalysts. The investment firm said it was now including the CTX320 and CTX310 in vivo ...

Evercore ISI has upgraded CRISPR Therapeutics (NASDAQ:CRSP) to Outperform, citing multiple upcoming catalysts that could drive the stock higher. The firm is now factoring in CTX320 and CTX310 in ...