X-linked myopathy with excessive autophagy (XMEA) is a rare disease for which pre-clinical models lack, challenging the ability to understand mechanisms and therapies. The use of the zebrafish to ...

Autophagy is a process by which cellular material is degraded by lysosomes or vacuoles and recycled. Several autophagy pathways operate within a cell, including macroautophagy, microautophagy and ...

Endogenous interactomes of MFN1 and MFN2 provide novel insights into interorganelle communication and autophagy. Autophagy , 2024; 1 DOI: 10.1080/15548627.2024.2440843 Cite This Page : ...

More information: Isabel Gordaliza-Alaguero et al, Endogenous interactomes of MFN1 and MFN2 provide novel insights into interorganelle communication and autophagy, Autophagy (2024). DOI: 10.1080 ...

Compared with young macrophages, old macrophages accumulated more lipid droplets upon lipid loading with the pro-atherogenic lipoprotein aggregated LDL (low-density lipoprotein), accompanied by a ...

Korea Bioactive Natural Material Bank, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea ...

Key Laboratory of Functional Polymer Materials of Ministry of Education, State Key Laboratory of Medicinal Chemical Biology, Institute of Polymer Chemistry and College of Chemistry, Nankai University, ...

Cheng et al. have now designed autophagy-inducing antibodies (AUTABs) that promote internalization and lysosomal degradation of their target cell surface receptor through autophagy. Autophagy ...

Zebrafish are unassuming and undemanding. Almost every child knows that – at least any child that has kept fish in an aquarium. Since the beginning of the 20th century, these fish have been one of the ...

Recently, there has been a growing appreciation for the existence of cellular plasticity in the adult islet. This study probes this phenomenon by exploiting the zebrafish experimental model, which has ...

We also describe how these pathways converge onto autophagy, a catabolic process that functions to recycle dysfunctional cellular material and maintains energy homeostasis. Finally, we consider ...