Fatty pancreas disease, characterized by intra-pancreatic fat deposition, is more prevalent than diabetes, pancreatitis, and ...

The study used innovative technology that maps RNA molecules which are the basis for translating the genome into proteins.

The new study, “insulin resistance increases TNBC aggressiveness and brain metastasis via adipocyte-derived exosomes,” published in Molecular Cancer Research, a journal of the American Association for ...

Mechanistically, icosabutate improved fibrosis independent of reductions in liver fat or body weight, emphasizing its unique mechanism and promise for combination with GLP-1RAs to optimize both ...

Adipose ALK7 silencing reduced fat mass by 50% while preserving lean mass. Similar to INHBE silencing in hepatocytes, ALK7 silencing in adipocytes enhanced catecholamine sensitivity, increasing lipid ...

ZyVersa Therapeutics (ZVSA) highlights newly published data demonstrating cardioprotective effects and improvements in metabolic parameters ...

2025 has gotten off to a choppy start as some of the most valuable U.S.-based companies are dragging down the major stock market indexes. But getting caught up in short-term market movements is a ...

Pli­ant Ther­a­peu­tics has of­fi­cial­ly dis­con­tin­ued a mid-stage study of its chron­ic lung dis­ease treat­ment, less than a month af­ter the tri­al’s safe­ty board rec­om ...

Objective: Graves’ orbitopathy (GO) is characterized by increased production of proinflammatory cytokines and hyaluronic acid by fibroblasts and their differentiation into adipocytes in response to ...

Early in his career, Collins discovered the gene that causes cystic fibrosis, which helped lead years later to effective treatment for the lung disease. He credited the discovery to an NIH grant ...

Vertex Pharmaceuticals (NASDAQ:VRTX) announced Friday that an expert panel of the EU drug regulator, the European Medicines Agency (EMA), endorsed its twice-daily cystic fibrosis medication ...

To him, the company’s potential in chronic lymphocytic leukemia is akin to two other legendary Big Biotech stories—Gilead in HIV and Vertex in cystic fibrosis. Oyler may not be exaggerating.