The study used innovative technology that maps RNA molecules which are the basis for translating the genome into proteins.

Fibrosis is the formation of fibrous connective tissue in response to injury. It is characterized by the accumulation of extracellular matrix components, particularly collagen, at the site of injury.

Cystic fibrosis (CF) treatment typically involves procedures and medications that help clear the airways. Other treatments may include antibiotics, pancreatic enzymes, a high-calorie diet, and ...

Epicardial adipose tissue (EAT) lies in direct contact with the myocardium, influencing adjacent myocardial tissue through adipokine signaling, adipocyte infiltration, and fibrotic remodeling in ...

we found subpopulations of adipocytes, characterized here for the first time, that express RNA molecules indicating unique functions, such as regulation of inflammatory processes, blood vessel ...

Maternal stress is a major risk factor for preterm birth (PTB), with recent mouse studies highlighting the role of FKBP51 in ...

Metabolomics was used to further explore differences in fibroblasts by obesity status. Results We identified multiple subclusters of fibroblasts, macrophages, adipocytes and endothelial cells with ...

Fibrosis involves an overgrowth of fibroblasts within an organ, together with uncontrolled elaboration of extracellular matrix protein and deposition of proteases, accompanied by the production of ...

Multiple pathways lead from the visceral adipocyte to myocardial hypertrophy, inflammation, and fibrosis. Although weight loss drugs such as tirzepatide combat these effects by reducing adipocytes ...