Despite its physiological function, dysregulation of the R-loop leads to DNA replication stress and excessive inflammation and is associated with AML pathophysiology. Mutations of cellular RNA-binding ...

Contributors Conception and design: CMT, AY, CL and AML-B. Acquisition of data, analysis and interpretation of data: CMT, CL and AML-B. Drafting the article or revising it critically for important ...

In contrast, since disseminated intravascular coagulation (DIC) is far less frequent in patients with non-APL acute myeloid leukemia (AML), the pathophysiology of AML-associated hemorrhagic disorders ...

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Radiation therapy uses high-energy radiation to kill cancer cells. It is usually not part of the main treatment for people with acute myeloid leukemia (AML), but there are a few instances in which it ...

Legal drafters, policy makers, financial sector AML/CFT supervisors, supervisors of designated non-financial businesses and professions, financial intelligence unit officials, criminal justice ...

The FDA granted fast track designation to AUTX-703 for the treatment of patients with relapsed/refractory acute myelogenous leukemia (R/R AML). Preclinical studies demonstrated dose-dependent survival ...