These include three discrete pathways for the excision of damaged bases, called base excision repair, mismatch repair and nucleotide excision repair (NER). NER in human cells is a complex ...

On the other hand, treatment of neuronal cultured cells with 1-methyl 4- phenyl 1, 2, 3, 6-tetrahydropyridine (MPTP ... Nucleo CMP Forte ® is a commercial nucleotide-based drug, consisting of ...

Both nucleoside and nucleotide analogues inhibit the HBV reverse transcriptase function ... To analyse the effect of IFN-λ3 on HBsAg levels, PLC/PRF/5 cells (5×10 4 cells per well) were treated with ...

ultrafast taxonomic profiling and genome querying for metagenomic samples by abundance-corrected minhash.

The polygenic score calculated using concordant single-nucleotide variants may be a method to evaluate risk for alcohol use ...

Sionna including strong clinical execution across multiple programs. Encouraging interim Phase 1 data for SION-719 and SION-451, our highly potent nucleotide-binding domain 1 stabilizers, showed that ...

The building blocks of life on Earth may have been fueled by tiny sparks hopping between water droplets.

Toribio Rodríguez de Mendoza National University researchers conducted a genomic analysis of fine aroma cocoa from northern ...

This short manuscript uses mutation counts in phylogenies of millions of SARS-CoV-2 genomes to show that mutation rates systematically differ between regions that are paired or unpaired in the ...

Atea Pharmaceuticals, Inc. (Nasdaq: AVIR) (Atea or Company), a clinical-stage biopharmaceutical company engaged in the ...

School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing 211166, China ...