Both nucleoside and nucleotide analogues inhibit the HBV reverse transcriptase function ... To analyse the effect of IFN-λ3 on HBsAg levels, PLC/PRF/5 cells (5×10 4 cells per well) were treated with ...

The polygenic score calculated using concordant single-nucleotide variants may be a method to evaluate risk for alcohol use ...

Sionna including strong clinical execution across multiple programs. Encouraging interim Phase 1 data for SION-719 and SION-451, our highly potent nucleotide-binding domain 1 stabilizers, showed that ...

The building blocks of life on Earth may have been fueled by tiny sparks hopping between water droplets.

Toribio Rodríguez de Mendoza National University researchers conducted a genomic analysis of fine aroma cocoa from northern ...

UCB, a global biopharmaceutical company, today announced positive data from studies involving its investigational pyrimidine nucleoside therapy, doxecitine (dC) and doxribtimine (dT), in people living ...

Phase 1 MAD dosing completed for SION-451 and final MAD cohort of SION-719 planned; Interim data in healthy volunteers show ...

UCB, a global biopharmaceutical company, today announced positive data from studies involving its investigational pyrimidine nucleoside therapy, doxecitine (dC) and doxribtimine (dT), in people living ...

Region Genetic Association Analysis of Breast Cancer Patients With and Without Persistent Postsurgical Neuropathic Pain,” ...

Based upon a successful engagement with the US Food and Drug Administration (FDA) at the End-of-Phase 2 meeting in January 2025, Atea is initiating a global Phase 3 program and expects patient ...

Atea Pharmaceuticals, Inc. (Nasdaq: AVIR) (Atea or Company) a clinical-stage biopharmaceutical company engaged in the discovery and development of oral antiviral ...

They also show that models learned from nonsynonymous mutations and from out-of-frame sequences are different, prompting new questions about germinal center function. Strengths of the study include an ...