The platform’s scalability, rapid production and relatively straightforward manufacturing process mean that mRNA therapeutics are a powerful alternative to traditional small molecule drugs and DNA ...

An in-depth analysis of this transferred mRNA revealed that mRNAs coding for molecules related to transcription, translation, and stress response were transferred from mouse cells to human cells. They ...

This suggests that mRNA moving between different mammalian ... The team also identified several key transcription factors involved in this process, with essential functions for pluripotent state ...

mRNA and LNPs moving forward According to Tam ... zinc-finger proteins (ZNFs), or transcription activator-like effector nucleases (TALEN). This could enable a type of therapy that would precisely ...

Kennedy Jr. is considering pulling funding for its bird flu vaccine. Is MRNA stock a sell? Investing.com -- Citi has expanded its biopharmaceutical research coverage, initiating coverage on seven ...

“Larger mRNA-based therapeutics are synthesised by in vitro transcription, which is not amenable to extensive nucleotide modifications and thus have poor stability when administered into the bod ...

During splicing, which occurs after transcription (i.e., the synthesis of RNA from a DNA template), the introns are removed and the exons are joined, or spliced together.

LncRNAs and circRNAs are key regulators of gene expression, influencing disease mechanisms and offering potential as ...

A single molecular switch is essential for blood stem cells to enter an activated, regenerative state in which they produce ...

This paper presents the important finding that BNIP3/NIX, a mitophagy receptor, and its binding to ATG18 are required for mitophagy during muscle cell reorganization in Drosophila. Although the ...