This study shows that engineered E. coli Nissle 1917 producing indole-3-acetic acid (IAA), an AhR agonist, modulate the tumor ...

Basophils trigger a cytokine cascade that improves antitumor immunity in mice, offering potential targets for cancer ...

From the approval of the first immune checkpoint inhibitors to the development of chimeric antigen receptor T cells, immunotherapy has demonstrated ...

However, 25-hydroxycholesterol prevents this inhibition, and therefore enables better activation of anti-tumor immunity. Prof. Hugues' team then deleted this enzyme in mouse lymphatic endothelial ...

In a nutshell Aspirin may help prevent cancer from spreading by stopping platelets from producing thromboxane A2 (TXA2), ...

A new review article published in Genes & Diseases sheds light on the complex molecular mechanisms through which ...

Aspirin's potential role in slowing cancer spread is gaining attention, with research suggesting its anti-inflammatory ...

Additional Phase 2 data for vilastobart,a tumor-activated, Fc-enhanced anti-CTLA-4, in combination with atezolizumab in patients with MSS CRC ...

Pancreatic cancer that spreads to the liver is especially difficult to treat because the liver naturally suppresses immune ...

ELF4, a transcription factor belonging to the ETS family, has emerged as a pivotal regulator in cell differentiation, immune system function, and cancer progression. This newly published review ...