Polymerization of tubulin dimers to form microtubules is one of the key events in cell proliferation. The inhibition of this event has long been recognized as a potential treatment option for various ...

Crystal Structure of the Cyclostreptin-Tubulin Adduct: Implications for Tubulin Activation by Taxane-Site Ligands. International Journal of Molecular Sciences 2019, 20 (6) , 1392. DOI: ...

Tau tubulin kinases (TTBKs) activate cyclin-dependent kinase 5 (Cdk5) and glycogen synthase kinase 3 beta (GSK3b), two tau kinases, and phosphorylate collapsin response mediator protein 2 (pCRMP2), ...

Changes Affecting Organization Structure. Adopting a new organizational structure often requires a serious commitment of company resources, so businesses don't undertake it lightly.

Mintzberg's Five Types of Organizational Structure By Steve Milano , Contributor An organizational structure helps companies assign duties and responsibilities to various staff and departments.

Scientists have discovered how to turn molecules made by everyday toxic mold into highly effective cancer-fighting drugs.

Structure-based drug design is the design and optimization of a chemical structure with the goal of identifying a compound suitable for clinical testing — a drug candidate. It is based on ...

A fire near Prater Way in the 2500 block of D Street in Sparks burned a debris pile and part of a structure Monday, June 2, sending two people to the hospital, authorities said. About 5:30 p.m ...

Discover Expo 2025 Osaka's Grand Ring, the world's largest wooden structure, showcasing innovative architecture and diverse global themes. Projects Images Products & BIM Professionals News Archive ...

GLOUCESTER, Va. (WAVY) — Abingdon Volunteer Fire and Rescue responded to a commercial structure fire on George Washington Memorial Highway Wednesday night. According to officials, around 9:50… ...

A raging fire erupted from an outbuilding next to the 10 Freeway in Palms, causing an explosion and heavily impacting eastbound traffic on Sunday evening. The Los Angeles Fire Department first ...