and cytokine TGF-β. The presence of the analytes was detected and quantified using a high throughput custom Quantibody multiplex enzyme-linked immunosorbent assay (ELISA) (RayBiotech) and the data ...

Although transforming growth factor (TGF)-β is known to be involved in the formation of KS and HS, the molecular mechanisms responsible for its activation remain unclear. In this study we investigated ...

Bone morphogenetic protein (BMP)-9 is a member of the transforming growth factor (TGF)-β family of cytokines, is produced by the liver and is constantly secreted into the blood stream. BMP-9 acts ...

肝脏巨噬细胞在调节肝细胞代谢和维持肝脏免疫耐受方面发挥核心作用。正常生理条件下，肝脏巨噬细胞倾向于 M2 表型，可通过分泌白细胞介素（IL）-4 和 IL-13 抑制炎症。然而，在 NAFLD 进展时，肝星状细胞激活、血液中脂多糖水平升高以及 FFA 激活炎症小体等变化，会刺激炎症发生，增加分泌促炎细胞因子的 M1 巨噬细胞比例。

Here the authors report that NPC1 prevents ubiquitylation and degradation of TGF-β receptor 1, leading to activation of the TGF-β pathway and hepatocellular carcinoma progression.

【导读】TREM2是一种主要在髓样细胞表面表达的受体，是病理诱导免疫信号传导中的一个主要枢纽基因。然而，其在肝细胞癌（HCC）中的功能仍存在争议。1月21日，新疆石河子大学研究团队在期刊《Journal of Experimental & Clinical Cancer Research》上发表了研究论文，题为“TREM2 promotes the formation of a tumor-sup ...

Dividend Yield: 5.6% based on the share price at the end of 2024. Elisa Oyj (ELMUY) reported a revenue increase of 2.9% in Q4 2024, marking the best quarter for revenue growth during the year.

"Q4 was a continuation of solid good development," he remarked. Elisa expects revenue and comparable EBITDA for 2025 to be at the same level or slightly higher than 2024. CapEx to sales is ...