That increased basal signaling via PI3K in the hypothalamus was ineffective in suppressing food intake suggests that cold exposure blocks signal transduction downstream of Akt as well.

STIM1-mediated NFAT signaling synergizes with STAT1 to control T-bet expression and T H 1 differentiation Feske and colleagues show how STIM- and ORAI-dependent calcium activation of NFAT plus IFN ...

The Fellows of the AACR Academy have elected Elaine V. Fuchs, PhD, FAACR, as their next President. She will assume the ...

After autophagy was blocked, the therapeutic effect of BSP was reversed. In addition, BSP activated the PI3K/AKT signaling pathway. Discussion: Studies have shown that BSP induces autophagy by ...

A new review article highlights the transformative role of circular RNA (circRNA) in cancer, revealing its potential as both ...

Bacteria need to be able to adapt to the changing and challenging environments in which they live to survive and multiply. One of the genetic processes by which they do this is transduction. In this ...

This is where microwave-to-optical transduction comes into play ... that not only is the transducer capable of converting the signal that reads out the qubit, but that the qubit can also be ...

2025年3月3日，海军医科大学曹雪涛院士的研究团队在期刊《Signal Transduction and Targeted Therapy》上发表了题为“Neoleukin-2/15-armored CAR-NK cells sustain superior therapeutic efficacy in solid tumors via c-Myc/NRF1 activation”的研究论文。

2016). This study identified many differentially methylated genes in Dup15q compared to control brains with functions in voltage-gated ion channels, cell adhesion, signal transduction, and ...

组蛋白修饰在癌症的发生和发展过程中起着关键作用，它就像一把 “分子开关”，通过对染色质结构和基因转录的调控，影响着细胞的各种行为。EBV 感染会引起组蛋白修饰的改变，然而，在 EBV 相关的上皮肿瘤中，具体涉及哪些组蛋白修饰因子以及它们的致癌机制，依旧是未解之谜。