The Despicable Me franchise centers on Gru, a super-villain (who later becomes a dad and superhero); his yellow-coloured Minions; and his three orphan girls, Margo, Edith and Agnes.

Taking place during the events of John Wick: Chapter 3 – Parabellum, the film follows Eve Macarro (Ana de Armas) who is beginning her training in the assassin traditions of the Ruska Roma.