Alternative splicing (AS) of pre-mRNA plays a crucial role in tissue-specific gene regulation, with disease implications due to splicing defects. Predicting and manipulating AS can therefore uncover ...

This isoform-centric microglia genomic atlas includes 35,879 novel human microglia isoforms identified by long-read RNA sequencing. A multi-ancestry quantitative trait locus meta-analysis of known ...

Genetics and Molecular Biology considera contribuições que apresentem os resultados de pesquisas originais nas áreas de genética, evolução e disciplinas científicas relacionadas. Genetics and ...

His scientific history began in the 60s when he approached molecular biology with the study of tRNA in the bacterium Streptomyces fradiae (Trentalance and Amaldi, 1965) but it was consolidated during ...

"AlphaFold is now routinely used in many biology labs. NuFold would be an RNA version of AlphaFold. So, in a way, we're extending the breakthrough of AlphaFold into the world of RNA, which has ...