Proteins are long molecules that must fold into complex three-dimensional structures to perform their cellular functions.
Researchers have identified a previously unknown bacterial protein, the structure of which is being used in the design of protein nanoparticles for the targeted delivery of anticancer drugs to tumors.
Medically reviewed by William Truswell, MD Collagen is a structural protein found in tissues in skin, hair, nails, cartilage, ...
A previously unknown protein in a family of bacteria found in soil and the human gut microbiome has been discovered – which could help drug delivery in cancer treatment.
Proteins in cells are highly flexible and often exist in multiple conformations, each with unique abilities to bind ligands. These conformations are regulated by the organism to control protein ...
As such, their structure can generally be predicted ... The three proteins thus behave similarly to the natural proteins that form the shells of viruses or support the formation of vesicles ...
Researchers say structure reveals many new ways to change PINK1, essentially switching it on, which will be "life-changing" for people with Parkinson’s disease.
However, predicting a single protein structure from its amino acid sequence is like looking at a single frame of a movie—it offers only a snapshot of a highly flexible molecule. Biomolecular ...
Protein structure predictions are bioinformatic analyses that produce predicted protein structures automatically using the protein amino acid sequence. Protein structures are important because ...
“Experimental protein-structure prediction can take about the ... which provides an environmental benefit in the form of a reduced carbon footprint. Isomorphic Labs is already collaborating ...