Recent work in The EMBO Journal describes a new hybrid post-translational modification of proteins, composed of a poly-ubiquitin chain that is attached to a target protein via a mono-ADP-ribose (MAR) ...

An effective HIV-1 vaccine must therefore elicit antibodies that can neutralize many variants of the virus. While broadly neutralizing antibodies (bnAbs) have been isolated from HIV-1 infected ...

The study shows that boosting mucin-type O-glycosylation in aged mice reinforces the blood-brain barrier and improves memory, ...

State Key Laboratory of Common Mechanism Research for Major Disease, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China ...

但希望之光已然显现：研究者通过腺相关病毒（AAV）基因治疗，将衰老小鼠脑血管的糖萼厚度恢复83%，不仅逆转血管渗漏，更让20月龄老年鼠在迷宫测试中展现超越年轻组的空间记忆能力。这项颠覆性发现不仅重新定义了血脑屏障的防御机制，更为对抗阿尔茨海默病开辟了全新治疗维度：修复纳米级的糖萼结构，或将成为阻止大脑"塌方式衰老"的关键突破口。

In Karen Thompson Walker’s latest novel, “The Strange Case of Jane O.,” a patient’s unusual symptoms suggest metaphysical mysteries. By Leah Greenblatt Leah Greenblatt is an editor at The ...

FROM the mind of Co Roscommon-born comedian and actor Chris O’Dowd, Small Town Big Story is described as “a very dramatic comedy set in a village full of secrets on the border of Ireland and ...

Chantal Kreviazuk, the Canadian Grammy-award winning singer, changed the lyrics to O Canada at the 4 Nations Face-Off game against the United States on Thursday in response to repeated comments ...