Monocytes and macrophages are myeloid cells that have important innate immune functions. Macrophages reside in tissues and respond to infection by producing inflammatory mediators and engulfing ...

BACKGROUND: Despite the high morbidity and mortality of heart failure with preserved ejection fraction (HFpEF), treatment ...

Innate immune systems, especially tumor-associated macrophages (TAMs), can both cooperate with chemotherapy and block its effects (5). Circulating monocytes are precursors for the majority of TAMs ...

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Aortic dissection is a life-threatening condition with complex immunological underpinnings. This article ...

Here the authors measure metabolic changes in human monocytes from different aged donors and find enhanced oxidative phosphorylation fueling myeloid differentiation in neonates which contrasts ...

Myeloid cells such as dendritic cells and macrophages actively modulate tissue inflammatory ... In this application note, explore how scientists can couple a serum-free medium with a xeno-free serum ...

This article explores common challenges faced by flow cytometry users, such as fluorochrome selection, the utility of tandem ...

The new findings are the first to describe distributions and perturbations of low-density granulocyte and normal-density neutrophil subsets in myelodysplastic syndromes (MDS), acute myeloid leukemia ...

Analysis of 55,564 cells revealed separate clustering of TN-JDM cells within monocyte, NK, CD8 + effector T and naïve B populations. The proportion of CD16 + monocytes was reduced in TN-JDM, and naïve ...

Monocytes are considered to be recruited to the intestine ... Besides the temporal changes, we investigated the differences in proinflammatory markers, myeloid cell subsets and macrophage dynamics ...