Repeated brain injury resulted in SOD1-ALS mice showing greater weight loss, an earlier tremor in the hind limbs, and ...

The mouse model closely mimics the specific dysferlin mutation and resulting disease, and enabled the researchers to evaluate how the complete therapy works—taking muscle stem cells, correcting ...

A team of stem cell scientists have successfully used embryonic stem cell engineering to create a bi-paternal mouse—a mouse ...

In two new papers, researchers from The Jackson Laboratory (JAX) report the successful use of two approaches -- gene therapy ...

2005). Age-dependent increase in total tau measured in the cerebral spinal fluid (personal communication, reMYND). These transgenic mice overexpress human tau, specifically the 4R/2N isoform, bearing ...

"Although mutations in the envelope proteins contribute to the adaptation, they are not solely responsible for the phenotype." The virus' adaptation to mouse cells, which has been demonstrated ...

Scientists say identification of two epigenetically different states in mouse model opens door to "entirely new world of ...

"The mutation-containing HSCs give rise to proinflammatory ... to the bad proteins that hurt normal cells." The LJI team used mouse models with mutated ASXL1 to solve this mystery.

Silexion Therapeutics Corp. (NASDAQ:SLXN) released new preclinical data for SIL-204, its next-generation siRNA therapeutic ...

Silexion Therapeutics (SLXN) announced new preclinical data for SIL-204, its next-generation siRNA therapeutic candidate. The findings ...