A non-protein amino acid homocysteine, alongside high glucose and other key proteins, could hamper the function of immunity-providing white blood cells, leading to complications associated with ...

With the use of modified amino acids, MilliporeSigma, a Merck KGaA company, has developed a means to simplify the fed-batch process in biomanufacturing. Merck won the 2018 CPhI Pharma Award for ...

A metal-free ribonucleotide reductase--an enzyme required for DNA replication--from bacterial pathogens uses a post-translationally modified amino acid (pictured) to initiate an essential DNA ...

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To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian ...

Synthetically modified amino acids provide the starting point for new medicines University of Bristol Press release issued: 15 October 2018 Amino acids are the building blocks of proteins, and ...

In this system proteins during synthesis are “tagged” with an amino acid, which is, under normal conditions, not present in these cells. In order to label proteins in a particular cell type ...

Scientists from Yale have devised a way to ensure genetically modified organisms (GMO s) can be safely confined in the environment, overcoming a major obstacle to widespread use of GMO s in ...

A new intracellular protein editing method enables rapid, site-specific incorporation of chemically modified amino acids or tags into endogenous proteins in live mammalian cells with minimal ...

To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian ...

To combat this, the researchers chemically modified the amino acids and peptides using the heating-quenching procedure used in glass manufacturing. This is when materials for the glass are heated ...