Stop the Spread. Injecting saline into mouse kidneys did not affect the left or right substantia nigra (top). Injecting fibrils of α-synuclein ablated about half of the dopaminergic neurons (middle ...
Using α-syn fibril-induced PD model, researchers aimed to restore the degenerated dopaminergic neurons in the substantia nigra of the midbrain by the wireless DBS nanosystem. After stereotactic ...
They also measured electrophysiological signals in midbrain organoids, demonstrating the versatility of the technology. Additionally, they monitored signal modulations induced by various drugs ...
Departments of Psychiatry and Neurology, Division of Molecular Therapeutics, New York State Psychiatric Institute, Columbia University Medical Center, New York, New York 10032, United States ...
The mitochondrion is a key player in cellular function and dysfunctional mitochondria have been implicated in a number of disorders as well as in the process of normal ageing. Our research group is ...